MMP17 antibody (C-Term)

Catalog No. ABIN2789884

The Rabbit Polyclonal anti-MMP17 antibody (ABIN2789884) specifically detects MMP17 in WB. The antibody is reactive with Human, Cow and Horse samples.

Quick Overview for MMP17 antibody (C-Term) (ABIN2789884)

Target: MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

Reactivity: Human, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP17 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MMP17 Antibody

Binding Specificity: C-Term

Purpose: MMP17 Antibody - C-terminal region

Sequence: YPQSTARDWL VCGDSQADGS VAAGVDAAEG PRAPPGQHDQ SRSEDGYEVC

Predicted Reactivity: Cow: 79%, Horse: 93%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against MMP17. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64577-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MMP17

Target: MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

Alternative Name: MMP17

Background:

Background Information: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.

Gene Name: Matrix metallopeptidase 17 (membrane-inserted)

Alternative Symbols: MMP-17, MT4MMP, MTMMP4, MT4-MMP

Protein Name: Matrix metalloproteinase-17

Molecular Weight: 66kDa

Gene ID: 4326

NCBI Accession: NP_057239

UniProt: Q9ULZ9