USO1 antibody (C-Term)

Catalog No. ABIN2789890

This Rabbit Polyclonal antibody specifically detects USO1 in WB. It exhibits reactivity toward Human, Rat, Dog, Horse and Pig.

Quick Overview for USO1 antibody (C-Term) (ABIN2789890)

Target: USO1 (USO1 Homolog, Vesicle Docking Protein (USO1))

Reactivity: Human, Rat, Dog, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USO1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-USO1 Antibody

Binding Specificity: C-Term

Purpose: USO1 Antibody - C-terminal region

Sequence: QNEQLQTAVT QQVSQIQQHK DQYNLLKIQL GKDNQHQGSY SEGAQMNGIQ

Predicted Reactivity: Dog: 92%, Horse: 79%, Human: 100%, Pig: 77%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against USO1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64597-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for USO1

Target: USO1 (USO1 Homolog, Vesicle Docking Protein (USO1))

Alternative Name: USO1

Background:

Background Information: The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner.

Gene Name: USO1 vesicle docking protein homolog (yeast)

Alternative Symbols: TAP, VDP, P115

Protein Name: General vesicular transport factor p115

Molecular Weight: 108kDa

Gene ID: 8615

NCBI Accession: NP_003706

UniProt: O60763