NPR3 antibody (C-Term)

Catalog No. ABIN2789944

The Rabbit Polyclonal anti-NPR3 antibody has been validated for WB. It is suitable to detect NPR3 in samples from Human, Rat, Mouse, Cow, Dog, Horse, Rabbit and Pig.

Quick Overview for NPR3 antibody (C-Term) (ABIN2789944)

Target: NPR3 (Atrial Natriuretic Peptide Receptor 3 (NPR3))

Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPR3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NPR3 Antibody

Binding Specificity: C-Term

Sequence: LEESAVTGIV VGALLGAGLL MAFYFFRKKY RITIERRTQQ EESNLGKHRE

Predicted Reactivity: Cow: 86%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against NPR3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 324 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NPR3

Target: NPR3 (Atrial Natriuretic Peptide Receptor 3 (NPR3))

Alternative Name: NPR3

Background: This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ANPRC, GUCY2B, NPRC, ANP-C, NPR-C, ANPR-C, C5orf23
Protein Interaction Partner: NPPC, NPPB, NPPA, UBC, NPR3,
Protein Size: 324

Molecular Weight: 37 kDa

Gene ID: 4883

NCBI Accession: NM_001204376, NP_001191305

UniProt: E7EPG9

Pathways: cAMP Metabolic Process