NPR3 antibody

Catalog No. ABIN2856727

This Rabbit Polyclonal antibody specifically detects NPR3 in WB, IF, ICC and IHC (p). It exhibits reactivity toward Human.

Quick Overview for NPR3 antibody (ABIN2856727)

Target: NPR3 (Atrial Natriuretic Peptide Receptor 3 (NPR3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPR3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-NPR3 Antibody

Cross-Reactivity: Chicken, Human, Mouse, Rabbit, Rat

Characteristics: Rabbit polyclonal antibody to NPR-C (natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C))
NPR-C antibody [N3C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human NPR-C. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.81 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for NPR3

Target: NPR3 (Atrial Natriuretic Peptide Receptor 3 (NPR3))

Alternative Name: natriuretic peptide receptor 3

Background: The family of natriuretic peptides (see MIM 108780) elicit a number of vascular, renal, and endocrine effects that are important in the maintenance of blood pressure and extracellular fluid volume. These effects are mediated by specific binding of the peptides to cell surface receptors in the vasculature, kidney, adrenal, and brain.[supplied by OMIM]

Cellular Localization: Membrane

Molecular Weight: 60 kDa

Gene ID: 4883

UniProt: P17342

Pathways: cAMP Metabolic Process