BMP8B antibody (N-Term)

Catalog No. ABIN2789952

This Rabbit Polyclonal antibody specifically detects BMP8B in WB. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Rabbit, Dog, Horse, Cow and Zebrafish (Danio rerio).

Quick Overview for BMP8B antibody (N-Term) (ABIN2789952)

Target: BMP8B (BMP8) (Bone Morphogenetic Protein 8B (BMP8))

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Dog, Horse, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP8B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BMP8B Antibody

Binding Specificity: N-Term

Purpose: BMP8B Antibody - N-terminal region

Sequence: CPQRRLGARE RRDVQREILA VLGLPGRPRP RAPPAASRLP ASAPLFMLDL

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 80%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 80%

Characteristics: This is a rabbit polyclonal antibody against BMP8B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human BMP8B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64755-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for BMP8B

Target: BMP8B (BMP8) (Bone Morphogenetic Protein 8B (BMP8))

Alternative Name: BMP8B

Background:

Background Information: The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity.

Gene Name: bone morphogenetic protein 8b

Alternative Symbols: OP2, BMP8

Protein Name: bone morphogenetic protein 8B

Molecular Weight: 38kDa

Gene ID: 656

NCBI Accession: NP_001711

UniProt: E7EMY8