WNK2 antibody (N-Term)

Catalog No. ABIN2790096

The Rabbit Polyclonal anti-WNK2 antibody (ABIN2790096) specifically detects WNK2 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Guinea Pig and Horse samples.

Quick Overview for WNK2 antibody (N-Term) (ABIN2790096)

Target: WNK2 (WNK Lysine Deficient Protein Kinase 2 (WNK2))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNK2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-WNK2 Antibody

Binding Specificity: N-Term

Purpose: WNK2 Antibody - N-terminal region

Sequence: APAPDGGPRE EAAATVRKED EGAAEAKPEP GRTRRDEPEE EEDDEDDLKA

Predicted Reactivity: Dog: 79%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against WNK2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human WNK2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65290-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for WNK2

Target: WNK2 (WNK Lysine Deficient Protein Kinase 2 (WNK2))

Alternative Name: WNK2

Background:

Background Information: The protein encoded by this gene is a cytoplasmic serine-threonine kinase that contains cysteine in place of the lysine found at the conserved ATP-binding location in subdomain II of protein kinases. Since this protein does have kinase activity, it is possible that another lysine in the kinase subdomain I can substitute for the missing conserved lysine.

Gene Name: WNK lysine deficient protein kinase 2

Alternative Symbols: PRKWNK2, NY-CO-43, SDCCAG43, P/OKcl.13

Protein Name: Serine/threonine-protein kinase WNK2 Ensembl ENSP00000378860

Molecular Weight: 234kDa

Gene ID: 65268

NCBI Accession: NP_006639

UniProt: F8W9F9

Pathways: Photoperiodism