APLF antibody (C-Term)

Catalog No. ABIN2790098

The Rabbit Polyclonal anti-APLF antibody is suitable to detect APLF in samples from Human, Mouse, Rat, Cow, Horse, Pig and Rabbit. It has been validated for WB.

Quick Overview for APLF antibody (C-Term) (ABIN2790098)

Target: APLF (Aprataxin and PNKP Like Factor (APLF))

Reactivity: Human, Mouse, Rat, Cow, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APLF antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-APLF Antibody

Binding Specificity: C-Term

Sequence: NVLDEDNDNV GQPNEYDLND SFLDDEEEDY EPTDEDSDWE PGKEDEEKED

Predicted Reactivity: Cow: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against APLF. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human APLF

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 511 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for APLF

Target: APLF (Aprataxin and PNKP Like Factor (APLF))

Alternative Name: APLF

Background: C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks.
Alias Symbols: APFL, C2orf13, FLJ16593, MGC47799, PALF, Xip1
Protein Interaction Partner: GMCL1, CHD1L, HIST3H3, PARP1, FBXO25, APP, XRCC5, LIG4, XRCC4, APLF, IRX5, XRCC1,
Protein Size: 511

Molecular Weight: 57 kDa

Gene ID: 200558

NCBI Accession: NM_173545, NP_775816

UniProt: Q8IW19

Pathways: DNA Damage Repair