COX7C antibody (N-Term)

Catalog No. ABIN2790102

The Rabbit Polyclonal anti-COX7C antibody is suitable to detect COX7C in samples from Human, Mouse, Rat, Pig, Cow and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for COX7C antibody (N-Term) (ABIN2790102)

Target: COX7C (Cytochrome C Oxidase Subunit VIIc (COX7C))

Reactivity: Human, Mouse, Rat, Pig, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX7C antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-COX7C Antibody

Binding Specificity: N-Term

Purpose: COX7C Antibody - N-terminal region

Sequence: SVVRRSHYEE GPGKNLPFSV ENKWSLLAKM CLYFGSAFAT PFLVVRHQLL

Predicted Reactivity: Cow: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against COX7C. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65314-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for COX7C

Target: COX7C (Cytochrome C Oxidase Subunit VIIc (COX7C))

Alternative Name: COX7C

Background:

Targeted Subunit: 7C, mitochondrial

Background Information: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIc, which shares 87 % and 85 % amino acid sequence identity with mouse and bovine COX VIIc, respectively, and is found in all tissues. A pseudogene COX7CP1 has been found on chromosome 13.

Gene Name: Cytochrome c oxidase subunit VIIc

Alternative Symbols: -

Protein Name: Cytochrome c oxidase subunit 7C, mitochondrial

Molecular Weight: 5kDa

Gene ID: 1350

NCBI Accession: NP_001858

UniProt: P15954