BCAS1 antibody (C-Term)

Catalog No. ABIN2790141

Product Details anti-BCAS1 Antibody

Target: BCAS1 (Breast Carcinoma Amplified Sequence 1 (BCAS1))

Binding Specificity: C-Term

Reactivity: Human, Dog, Rabbit, Cow, Guinea Pig, Horse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCAS1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KSVKEDSVPT GAEENTSDST EKTITPPEPE PTGAPQKGKE GSSKDKKSAA

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 91%, Horse: 92%, Human: 100%, Rabbit: 100%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against BCAS1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human BCAS1

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BCAS1

Target: BCAS1 (Breast Carcinoma Amplified Sequence 1 (BCAS1))

Alternative Name: BCAS1 (BCAS1 Products)

Synonyms: AIBC1 antibody, NABC1 antibody, 2210416M21Rik antibody, 9030223A09Rik antibody, AI841227 antibody, Band83 antibody, Pmes-2 antibody, BCAS1 antibody, MGC152145 antibody, breast carcinoma amplified sequence 1 antibody, BCAS1 antibody, Bcas1 antibody

Background: This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AIBC1, NABC1
Protein Size: 506

Molecular Weight: 55 kDa

Gene ID: 8537

NCBI Accession: NM_001316361, NP_001303290

UniProt: G3XAF7