BCAS1 antibody (C-Term)

Catalog No. ABIN2790141

The Rabbit Polyclonal anti-BCAS1 antibody (ABIN2790141) specifically detects BCAS1 in WB. The antibody is reactive with Human, Rat, Dog, Rabbit, Cow, Guinea Pig and Horse samples.

Quick Overview for BCAS1 antibody (C-Term) (ABIN2790141)

Target: BCAS1 (Breast Carcinoma Amplified Sequence 1 (BCAS1))

Reactivity: Human, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCAS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BCAS1 Antibody

Binding Specificity: C-Term

Purpose: BCAS1 Antibody - C-terminal region

Sequence: KSVKEDSVPT GAEENTSDST EKTITPPEPE PTGAPQKGKE GSSKDKKSAA

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 91%, Horse: 92%, Human: 100%, Rabbit: 100%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against BCAS1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human BCAS1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65410-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for BCAS1

Target: BCAS1 (Breast Carcinoma Amplified Sequence 1 (BCAS1))

Alternative Name: BCAS1

Background:

Background Information: This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: breast carcinoma amplified sequence 1

Alternative Symbols: AIBC1, NABC1, PMES-2

Protein Name: breast carcinoma-amplified sequence 1

Molecular Weight: 55kDa

Gene ID: 8537

NCBI Accession: NP_001303290

UniProt: G3XAF7