Intersectin 2 antibody (C-Term)

Catalog No. ABIN2790154

This Rabbit Polyclonal antibody specifically detects Intersectin 2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Pig, Cow, Dog, Horse and Rabbit.

Quick Overview for Intersectin 2 antibody (C-Term) (ABIN2790154)

Target: Intersectin 2 (ITSN2)

Reactivity: Human, Mouse, Rat, Pig, Cow, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Intersectin 2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Intersectin 2 Antibody

Binding Specificity: C-Term

Purpose: ITSN2 Antibody - C-terminal region

Sequence: TFTEGEEILV TQKDGEWWTG SIGDRSGIFP SNYVKPKDQE SFGSASKSGA

Predicted Reactivity: Cow: 86%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 100%, Rabbit: 93%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against ITSN2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ITSN2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65456-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Intersectin 2

Target: Intersectin 2 (ITSN2)

Alternative Name: ITSN2

Background:

Background Information: This gene encodes a cytoplasmic protein which contains SH3 domains. This protein is a member of a family of proteins involved in clathrin-mediated endocytosis. Intersectin 2 is thought to regulate the formation of clathrin-coated vesicles and also may function in the induction of T cell antigen receptor (TCR) endocytosis. Alternatively spliced transcript variants have been found for this gene that encode three distinct isoforms. Additional variants have been found but their full length nature has not been determined.

Gene Name: Intersectin 2

Alternative Symbols: SWA, SWAP, SH3D1B, SH3P18, PRO2015

Molecular Weight: 142kDa

Gene ID: 50618

NCBI Accession: NP_671494

UniProt: E7EUQ1