CFHR5 antibody (N-Term)

Catalog No. ABIN2790204

The Rabbit Polyclonal anti-CFHR5 antibody is suitable to detect CFHR5 in samples from Human. It has been validated for WB.

Quick Overview for CFHR5 antibody (N-Term) (ABIN2790204)

Target: CFHR5 (Complement Factor H-Related 5 (CFHR5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CFHR5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CFHR5 Antibody

Binding Specificity: N-Term

Purpose: CFHR5 Antibody - N-terminal region

Sequence: SCVERGWSTP PICSFTKGEC HVPILEANVD AQPKKESYKV GDVLKFSCRK

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CFHR5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CFHR5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65643-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CFHR5

Target: CFHR5 (Complement Factor H-Related 5 (CFHR5))

Alternative Name: CFHR5

Background:

Background Information: This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein.

Alternative Symbols: FHR5, CFHL5, FHR-5, CFHR5D

Protein Name: Complement factor H-related protein 5

Molecular Weight: 64kDa

Gene ID: 81494

NCBI Accession: NP_110414

UniProt: Q9BXR6