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Latrophilin 1 antibody (C-Term)

LPHN1 Reactivity: Rat, Human, Mouse, Cow, Dog, Guinea Pig, Horse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2790265
  • Target See all Latrophilin 1 (LPHN1) Antibodies
    Latrophilin 1 (LPHN1)
    Binding Specificity
    • 15
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 31
    • 22
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Rat, Human, Mouse, Cow, Dog, Guinea Pig, Horse
    Host
    • 35
    • 2
    Rabbit
    Clonality
    • 35
    • 2
    Polyclonal
    Conjugate
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Latrophilin 1 antibody is un-conjugated
    Application
    • 13
    • 13
    • 9
    • 7
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    YSLRSGDFPP GDGGPEPPRG RNLADAAAFE KMIISELVHN NLRGSSSAAK
    Predicted Reactivity
    Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against LPHN1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human LPHN1
    Top Product
    Discover our top product LPHN1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 839 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Latrophilin 1 (LPHN1)
    Alternative Name
    LPHN1 (LPHN1 Products)
    Synonyms
    LPHN1 antibody, CIRL1 antibody, CL1 antibody, LEC2 antibody, 2900070I05Rik antibody, AI182398 antibody, CLIBA antibody, Lec2 antibody, mKIAA0821 antibody, CL1BA antibody, adhesion G protein-coupled receptor L1 antibody, ADGRL1 antibody, Adgrl1 antibody
    Background
    This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane.
    Alias Symbols: CIRL1, CL1, LEC2
    Protein Interaction Partner: PSMA3, ELAVL1, UBC, CACNA1A, APC, ANKS1A, SHANK1, SHANK2, DLG4, DLG3, ROS1,
    Protein Size: 839
    Molecular Weight
    95 kDa
    Gene ID
    22859
    NCBI Accession
    NM_001008701
    UniProt
    O94910
    Pathways
    Synaptic Membrane, Synaptic Vesicle Exocytosis
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