SGPL1 antibody (C-Term)

Catalog No. ABIN2790344

The Rabbit Polyclonal anti-SGPL1 antibody is suitable to detect SGPL1 in samples from Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Goat, Guinea Pig and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for SGPL1 antibody (C-Term) (ABIN2790344)

Target: SGPL1 (Sphingosine-1-Phosphate Lyase 1 (SGPL1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Goat, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGPL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SGPL1 Antibody

Binding Specificity: C-Term

Purpose: SGPL1 Antibody - C-terminal region

Sequence: IHFCITLLHA RKRVAIQFLK DIRESVTQIM KNPKAKTTGM GAIYGMAQTT

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%

Characteristics: This is a rabbit polyclonal antibody against SGPL1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SGPL1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP66092-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SGPL1

Target: SGPL1 (Sphingosine-1-Phosphate Lyase 1 (SGPL1))

Alternative Name: SGPL1

Background:

Background Information: SGPL1 cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. SGPL1 elevates stress-induced ceramide production and apoptosis.

Alternative Symbols: SPL, S1PL, NPHS14

Protein Name: Sphingosine-1-phosphate lyase 1

Molecular Weight: 63kDa

Gene ID: 8879

NCBI Accession: NP_003892

UniProt: O95470

Pathways: Platelet-derived growth Factor Receptor Signaling