PDGFRL antibody (N-Term)

Catalog No. ABIN2790370

The Rabbit Polyclonal anti-PDGFRL antibody is suitable to detect PDGFRL in samples from Human, Rat, Cow, Horse and Pig. It has been validated for WB.

Quick Overview for PDGFRL antibody (N-Term) (ABIN2790370)

Target: PDGFRL (Platelet-Derived Growth Factor Receptor-Like (PDGFRL))

Reactivity: Human, Rat, Cow, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFRL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDGFRL Antibody

Binding Specificity: N-Term

Purpose: PDGFRL Antibody - N-terminal region

Sequence: KVKPKIPKMK DRDSANSAPK TQSIMMQVLD KGRFQKPAAT LSLLAGQTVE

Predicted Reactivity: Cow: 75%, Horse: 79%, Human: 100%, Pig: 79%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against PDGFRL. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PDGFRL

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP66236-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDGFRL

Target: PDGFRL (Platelet-Derived Growth Factor Receptor-Like (PDGFRL))

Alternative Name: PDGFRL

Background:

Background Information: This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor.

Alternative Symbols: PDGRL, PRLTS

Protein Name: Platelet-derived growth factor receptor-like protein

Molecular Weight: 38kDa

Gene ID: 5157

NCBI Accession: NP_006198

UniProt: Q15198

Pathways: Platelet-derived growth Factor Receptor Signaling