COASY antibody (C-Term)

Catalog No. ABIN2790465

This Rabbit Polyclonal antibody specifically detects COASY in WB. It exhibits reactivity toward Human, Mouse, Rat, Pig, Cow, Dog, Guinea Pig and Horse.

Quick Overview for COASY antibody (C-Term) (ABIN2790465)

Target: COASY (CoA Synthase (COASY))

Reactivity: Human, Mouse, Rat, Pig, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COASY antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-COASY Antibody

Binding Specificity: C-Term

Purpose: COASY Antibody - C-terminal region

Sequence: ETYRGGMAIN RFRLENDLEE LALYQIQLLK DLRHTENEED KVSSSSFRQR

Predicted Reactivity: Cow: 86%, Dog: 83%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 100%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against COASY. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human COASY

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP66543-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for COASY

Target: COASY (CoA Synthase (COASY))

Alternative Name: COASY

Background:

Background Information: Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. COASY is a bifunctional enzyme that catalyzes the 2 last steps in CoA synthesis. These activities are performed by 2 separate enzymes, phosphopantetheine adenylyltransferase and dephospho-CoA kinase, in prokaryotes.

Alternative Symbols: NBP, DPCK, PPAT, UKR1, NBIA6, PCH12, pOV-2

Protein Name: Bifunctional coenzyme A synthase

Molecular Weight: 65kDa

Gene ID: 80347

NCBI Accession: NP_001035997

UniProt: Q13057

Pathways: Ribonucleoside Biosynthetic Process