D2HGDH antibody (C-Term)
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- Target See all D2HGDH Antibodies
- D2HGDH (D-2-Hydroxyglutarate Dehydrogenase (D2HGDH))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Rabbit, Dog, Horse, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This D2HGDH antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- QESPFYVLIE TSGSNAGHDA EKLGHFLEHA LGSGLVTDGT MATDQRKVKM
- Predicted Reactivity
- Dog: 79%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 77%, Rabbit: 100%, Rat: 92%
- Characteristics
- This is a rabbit polyclonal antibody against D2HGDH. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human D2HGDH
- Top Product
- Discover our top product D2HGDH Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 521 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- D2HGDH (D-2-Hydroxyglutarate Dehydrogenase (D2HGDH))
- Alternative Name
- D2HGDH (D2HGDH Products)
- Synonyms
- AA408776 antibody, AA408778 antibody, AI325464 antibody, RGD1307976 antibody, D2HGD antibody, zgc:158661 antibody, D-2-hydroxyglutarate dehydrogenase antibody, D2hgdh antibody, D2HGDH antibody, d2hgdh antibody
- Background
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This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.
Alias Symbols: D2HGD, FLJ42195, MGC25181
Protein Interaction Partner: SUMO1, UBC,
Protein Size: 521 - Molecular Weight
- 55 kDa
- Gene ID
- 728294
- NCBI Accession
- NM_152783, NP_689996
- UniProt
- Q8N465
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