MEPCE antibody (Middle Region)

Catalog No. ABIN2790651

The Rabbit Polyclonal anti-MEPCE antibody (ABIN2790651) specifically detects MEPCE in WB. The antibody is reactive with Human, Rat, Dog, Guinea Pig and Rabbit samples.

Quick Overview for MEPCE antibody (Middle Region) (ABIN2790651)

Target: MEPCE (Methylphosphate Capping Enzyme (MEPCE))

Reactivity: Human, Rat, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEPCE antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MEPCE Antibody

Binding Specificity: Middle Region

Purpose: MEPCE Antibody - middle region

Sequence: HRHRGQHHQQ QQAAGGSESH PVPPTAPLTP LLHGEGASQQ PRHRGQNRDA

Predicted Reactivity: Dog: 79%, Guinea Pig: 86%, Human: 100%, Rabbit: 79%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against MEPCE. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human MEPCE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP67170-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MEPCE

Target: MEPCE (Methylphosphate Capping Enzyme (MEPCE))

Alternative Name: MEPCE

Background:

Background Information: MEPCE is a S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it.

Alternative Symbols: BCDIN3

Protein Name: 7SK snRNA methylphosphate capping enzyme

Molecular Weight: 76kDa

Gene ID: 56257

NCBI Accession: NP_062552

UniProt: Q7L2J0

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection