Deltex Homolog 4 antibody (C-Term)

Catalog No. ABIN2791002

Product Details anti-Deltex Homolog 4 Antibody

Target: Deltex Homolog 4 (DTX4) (Deltex Homolog 4 (Drosophila) (DTX4))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Rat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Deltex Homolog 4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LPVCLTRPPK LVLHPPPVSK SEIKSIPGVS NTSRKTTKKQ AKKGKTPEEV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against DTX4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DTX4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 619 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Deltex Homolog 4

Target: Deltex Homolog 4 (DTX4) (Deltex Homolog 4 (Drosophila) (DTX4))

Alternative Name: DTX4 (DTX4 Products)

Background: DTX4 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. It functions as an ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.
Alias Symbols: RNF155
Protein Interaction Partner: HSP90AA1, NLRP4, TBK1,
Protein Size: 619

Molecular Weight: 67 kDa

Gene ID: 23220

NCBI Accession: NM_015177, NP_055992

UniProt: Q9Y2E6

Pathways: Notch Signaling