TCTN2 antibody (N-Term)

Catalog No. ABIN2791187

The Rabbit Polyclonal anti-TCTN2 antibody is suitable to detect TCTN2 in samples from Human, Mouse, Rat, Horse and Pig. It has been validated for WB.

Quick Overview for TCTN2 antibody (N-Term) (ABIN2791187)

Target: TCTN2 (Tectonic Family Member 2 (TCTN2))

Reactivity: Human, Mouse, Rat, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCTN2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TCTN2 Antibody

Binding Specificity: N-Term

Purpose: TCTN2 Antibody - N-terminal region

Sequence: VIPGAVLEVT VRWKRGLDWC SSNETDSFSE SPCILQTLLV SASHNSSCSA

Predicted Reactivity: Horse: 92%, Human: 100%, Mouse: 77%, Pig: 92%, Rat: 77%

Characteristics: This is a rabbit polyclonal antibody against TCTN2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TCTN2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP68922-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TCTN2

Target: TCTN2 (Tectonic Family Member 2 (TCTN2))

Alternative Name: TCTN2

Background:

Background Information: This gene encodes a type I membrane protein that belongs to the tectonic family. Studies in mice suggest that this protein may be involved in hedgehog signaling, and essential for ciliogenesis. Mutations in this gene are associated with Meckel syndrome type 8. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative Symbols: MKS8, TECT2, JBTS24, C12orf38

Protein Name: Tectonic-2

Molecular Weight: 73kDa

Gene ID: 79867

NCBI Accession: NP_001137322

UniProt: Q96GX1

Pathways: Proton Transport