DRAXIN antibody (C-Term)

Catalog No. ABIN2791412

Product Details anti-DRAXIN Antibody

Target: DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))

Binding Specificity: C-Term

Reactivity: Human, Cow, Dog, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DRAXIN antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TLDMALFDWT DYEDLKPDGW PSAKKKEKHR GKLSSDGNET SPAEGEPCDH

Predicted Reactivity: Cow: 86%, Dog: 93%, Horse: 100%, Human: 100%, Pig: 86%

Characteristics: This is a rabbit polyclonal antibody against DRAXIN. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DRAXIN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 349 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DRAXIN

Target: DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))

Alternative Name: DRAXIN (DRAXIN Products)

Synonyms: C1orf187 antibody, draxin antibody, AGPA3119 antibody, UNQ3119 antibody, neucrin antibody, 2610109H07Rik antibody, MGC113312 antibody, dorsal inhibitory axon guidance protein antibody, DRAXIN antibody, Draxin antibody, draxin antibody

Background: DRAXIN is a chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. It acts as a chemorepulsive guidance protein for commissural axons during development and is able to inhibit or repel neurite outgrowth from dorsal spinal cord. DRAXIN inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
Alias Symbols: AGPA3119, UNQ3119, neucrin
Protein Size: 349

Molecular Weight: 36 kDa

Gene ID: 374946

NCBI Accession: NM_198545, NP_940947

UniProt: Q8NBI3