NUP62 antibody (Middle Region)

Catalog No. ABIN2791710

The Rabbit Polyclonal anti-NUP62 antibody is suitable to detect NUP62 in samples from Human, Mouse, Rat, Dog, Guinea Pig, Horse and Pig. It has been validated for WB.

Quick Overview for NUP62 antibody (Middle Region) (ABIN2791710)

Target: NUP62 (Nucleoporin 62kDa (NUP62))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP62 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NUP62 Antibody

Binding Specificity: Middle Region

Purpose: NUP62 Antibody - middle region

Sequence: TAPPGPGAAA GAAASSAMTY AQLESLINKW SLELEDQERH FLQQATQVNA

Predicted Reactivity: Dog: 85%, Guinea Pig: 77%, Horse: 77%, Human: 100%, Mouse: 77%, Pig: 85%, Rat: 77%

Characteristics: This is a rabbit polyclonal antibody against NUP62. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human NUP62

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP70972-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for NUP62

Target: NUP62 (Nucleoporin 62kDa (NUP62))

Alternative Name: NUP62

Background:

Background Information: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. NUP62 is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals.

Alternative Symbols: p62, IBSN, SNDI

Protein Name: Nuclear pore glycoprotein p62

Molecular Weight: 57kDa

Gene ID: 23636

NCBI Accession: NP_714941

UniProt: P37198

Pathways: EGFR Signaling Pathway, SARS-CoV-2 Protein Interactome