PIK3CB antibody (N-Term)

Catalog No. ABIN2792057

The Rabbit Polyclonal anti-PIK3CB antibody is suitable to detect PIK3CB in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Pig. It has been validated for WB.

Quick Overview for PIK3CB antibody (N-Term) (ABIN2792057)

Target: PIK3CB (Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide (PIK3CB))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIK3CB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PIK3CB Antibody

Binding Specificity: N-Term

Purpose: PIK3CB Antibody - N-terminal region

Sequence: ENATALHVKF PENKKQPYYY PPFDKSRGGK KFLPVLKEIL DRDPLSQLCE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PIK3CB. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human PIK3CB

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP72552-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PIK3CB

Target: PIK3CB (Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide (PIK3CB))

Alternative Name: PIK3CB

Background:

Background Information: This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants.

Gene Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

Alternative Symbols: PI3K, PIK3C1, P110BETA, PI3KBETA

Protein Name: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

Molecular Weight: 26kDa

Gene ID: 5291

NCBI Accession: NP_006210

UniProt: P42338