Transportin 3 antibody (C-Term)

Catalog No. ABIN2792069

The Rabbit Polyclonal anti-Transportin 3 antibody is suitable to detect Transportin 3 in samples from Human, Mouse, Rat, Cow, Pig, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for Transportin 3 antibody (C-Term) (ABIN2792069)

Target: Transportin 3 (TNPO3)

Reactivity: Human, Mouse, Rat, Cow, Pig, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Transportin 3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Transportin 3 Antibody

Binding Specificity: C-Term

Purpose: TNPO3 Antibody - C-terminal region

Sequence: LCIPTFQLLE QQNGLQNHPD TVDDLFRLAT RFIQRSPVTL LRSQVVIPIL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against TNPO3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TNPO3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP72799-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Transportin 3

Target: Transportin 3 (TNPO3)

Alternative Name: TNPO3

Background:

Background Information: The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene.

Alternative Symbols: IPO12, TRNSR, LGMD1F, LGMDD2, MTR10A, TRN-SR, TRN-SR2

Molecular Weight: 94kDa

Gene ID: 23534

UniProt: Q9Y5L0

Pathways: Protein targeting to Nucleus