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RIPK2 antibody (Receptor-Interacting Serine-threonine Kinase 2) (Middle Region) Primary Antibody

RIPK2 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit IF, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2792136
$389.00
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100 μL
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  • Target
    RIPK2
    Binding Specificity
    Middle Region
    • 14
    • 9
    • 8
    • 8
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
    • 89
    • 44
    • 24
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Host
    Rabbit
    Clonality
    Polyclonal
    Conjugate
    This RIPK2 antibody is un-conjugated
    • 58
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Application
    Immunofluorescence (IF), Western Blotting (WB)
    • 77
    • 49
    • 33
    • 11
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Sequence
    LRQERKRPLL DLHIELNGYM YDWNSRVSAK EKYYVWLQHT LRKKLILSYT
    Predicted Reactivity
    Cow: 85%, Dog: 85%, Guinea Pig: 78%, Horse: 85%, Human: 85%, Mouse: 78%, Rabbit: 84%, Rat: 78%
    Characteristics
    This is a rabbit polyclonal antibody against RIPK2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human RIPK2
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 540 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    RIPK2
    Alternative Name
    RIPK2 (RIPK2 Antibody Abstract)
    Synonyms
    RIPK2, 2210420D18Rik, CARD3, CARDIAK, CCK, D4Bwg0615e, RICK, RIP2, GIG30, receptor interacting serine/threonine kinase 2, receptor (TNFRSF)-interacting serine-threonine kinase 2, receptor-interacting serine-threonine kinase 2, RIPK2, Ripk2
    Background
    RIPK2 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. It contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CARD3, CARDIAK, CCK, GIG30, RICK, RIP2
    Protein Interaction Partner: RIPK2, XIAP, UBC, TRAF3, KDM3A, PRMT2, PELI3, NOD1, MAP3K7, CHUK, LRRK2, NOD2, TRAF4, TRAF6, MAP3K4, CASP12, NAT16, RNF31, RIPK1, MAVS, TRAF2, TAB2, TAB1, IKBKG, BIRC3, BIRC2, CARD16, CARD6, UBE2I, SMURF1, CFLAR, BCL10, TLR4, TLR2, TRAF5, CASP8, TRAF1, SM
    Protein Size: 540
    Molecular Weight
    61 kDa
    Gene ID
    8767
    NCBI Accession
    NM_003821, NP_003812
    UniProt
    O43353
    Pathways
    TCR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades
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