CDK2 antibody (C-Term)

Catalog No. ABIN2792150

This Rabbit Polyclonal antibody specifically detects CDK2 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Rabbit, Cow, Sheep, Zebrafish (Danio rerio), Goat and Guinea Pig.

Quick Overview for CDK2 antibody (C-Term) (ABIN2792150)

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Sheep, Zebrafish (Danio rerio), Goat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CDK2 Antibody

Binding Specificity: C-Term

Sequence: SKVVPPLDED GRSLLSQMLH YDPNKRISAK AALAHPFFQD VTKPVPHLRL

Predicted Reactivity: Cow: 100%, Goat: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 75%

Characteristics: This is a rabbit polyclonal antibody against CDK2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CDK2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 298 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDK2

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Alternative Name: CDK2

Background: Cdk2 is probably involved in the control of the cell cycle. It interacts with cyclins A, D, or E. Activity of cdk2 is maximal during S phase and G2.
Alias Symbols: p33(CDK2)
Protein Interaction Partner: MAPT, CDKN1A, CCNA2, VCP, SAMHD1, IMPDH2, CDK2, SKP1, FZR1, CKS2, CKS1B, CCNE2, GOLGA2, CREBBP, CDKN1C, CDKN1B, CCNE1, CDK13, SKP2, RBL2, RBL1, CCNB1, COPS5, PTMA, HIST1H1A, PRDX1, CCNJ, CDK7, CDK3, EP300, ATP1A1, MYBL2, MNAT1, HSPD1, HSP90AB1, HSP90AA1,
Protein Size: 298

Molecular Weight: 34 kDa

Gene ID: 1017

NCBI Accession: NM_001798, NP_001789

UniProt: P24941

Pathways: PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA