Cyclin A antibody (C-Term)

Catalog No. ABIN2792174

The Rabbit Polyclonal anti-Cyclin A antibody has been validated for WB. It is suitable to detect Cyclin A in samples from Human, Mouse, Rat, Cow, Rabbit, Zebrafish (Danio rerio), Dog, Pig and Horse.

Quick Overview for Cyclin A antibody (C-Term) (ABIN2792174)

Target: Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Zebrafish (Danio rerio), Dog, Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cyclin A Antibody

Binding Specificity: C-Term

Sequence: YTLESLKPCL MDLHQTYLKA PQHAQQSIRE KYKNSKYHGV SLLNPPETLN L

Predicted Reactivity: Cow: 100%, Dog: 91%, Horse: 91%, Human: 100%, Mouse: 91%, Pig: 100%, Rabbit: 100%, Rat: 91%, Zebrafish: 81%

Characteristics: This is a rabbit polyclonal antibody against CCNA2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CCNA2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 432 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cyclin A

Target: Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

Alternative Name: CCNA2

Background: Cyclin A is essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions.
Alias Symbols: CCN1, CCNA
Protein Interaction Partner: UBC, CDC20, Samhd1, BIRC6, ANAPC11, CDKN1A, CDK4, CDK2, CDK1, DYRK1A, DYRK1B, CDK3, CDKN1B, CDK5, TP73, RB1, POLA1, CTNNB1, NFYB, NFYA, CDK7, HIST1H1A, HIST1H1B, CDC6, BRCA2, TRIM33, RBL2, PRC1, Mdm2, CDT1, FZR1, CCNA2, SKP2, RAD23A, PSMD4, USP37, COPS5,
Protein Size: 432

Molecular Weight: 49 kDa

Gene ID: 890

NCBI Accession: NM_001237, NP_001228

UniProt: P20248

Pathways: PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA