CXCL14 antibody (Middle Region)

Catalog No. ABIN2792192

There are 3+ publications for this product available. The Rabbit Polyclonal anti-CXCL14 antibody is suitable to detect CXCL14 in samples from Rat, Dog, Cow, Horse and Guinea Pig. It has been validated for IHC and WB.

Quick Overview for CXCL14 antibody (Middle Region) (ABIN2792192)

Target: CXCL14 (Chemokine (C-X-C Motif) Ligand 14 (CXCL14))

Reactivity: Rat, Dog, Cow, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCL14 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-CXCL14 Antibody

Binding Specificity: Middle Region

Purpose: CXCL14 Antibody - middle region

Sequence: PHCEEKMVII TTKSVSRYRG QEHCLHPKLQ STKRFIKWYN AWNEKRRVYE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CXCL14. It was validated on Western Blot.

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CXCL14

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-CXCL14 antibody (ABIN2792192)

Lietz, Bayer, Ontikatze, Johrden, Tenbusch, Storcksdieck Genannt Bonsmann, Uberla, Dittmer, Wildner: "Codelivery of the chemokine CCL3 by an adenovirus-based vaccine improves protection from retrovirus infection." in: Journal of virology, Vol. 86, Issue 3, pp. 1706-16, (2012) (PubMed).

Perrone, Mattocks, Plummer, Chittur, Mohney, Vignola, Orentreich, Orentreich: "Genomic and metabolic responses to methionine-restricted and methionine-restricted, cysteine-supplemented diets in Fischer 344 rat inguinal adipose tissue, liver and quadriceps muscle." in: Journal of nutrigenetics and nutrigenomics, Vol. 5, Issue 3, pp. 132-57, (2012) (PubMed).

Takahashi, Takahashi, Takahashi, Zolotaryov, Hong, Iida, Okimura, Kaji, Chihara: "CXCL14 enhances insulin-dependent glucose uptake in adipocytes and is related to high-fat diet-induced obesity." in: Biochemical and biophysical research communications, Vol. 364, Issue 4, pp. 1037-42, (2007) (PubMed).

Target Details for CXCL14

Target: CXCL14 (Chemokine (C-X-C Motif) Ligand 14 (CXCL14))

Alternative Name: CXCL14

Background:

Background Information: CXCL14 belongs to the cytokine family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation.

Gene Name: Chemokine (C-X-C motif) ligand 14

Alternative Symbols: KEC, KS1, BMAC, BRAK, NJAC, MIP2G, MIP-2g, SCYB14

Protein Name: C-X-C motif chemokine 14

Molecular Weight: 9kDa

Gene ID: 9547

NCBI Accession: NP_004878

UniProt: O95715

Pathways: Autophagy