AIFM2 antibody (Middle Region)

Catalog No. ABIN2792236

The Rabbit Polyclonal anti-AIFM2 antibody (ABIN2792236) specifically detects AIFM2 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig and Rabbit samples.

Quick Overview for AIFM2 antibody (Middle Region) (ABIN2792236)

Target: AIFM2 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 2 (AIFM2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AIFM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-AIFM2 Antibody

Binding Specificity: Middle Region

Purpose: AIFM2 Antibody - middle region

Sequence: GALTFLLSMG RNDGVGQISG FYVGRLMVRL TKSRDLFVST SWKTMRQSPP

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Human: 100%, Mouse: 80%, Rabbit: 93%, Rat: 80%

Characteristics: This is a rabbit polyclonal antibody against AIFM2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AIFM2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for AIFM2

Target: AIFM2 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 2 (AIFM2))

Alternative Name: AIFM2

Background:

Background Information: AIFM2 has significant homology to NADH oxidoreductases and the apoptosis-inducing factor PDCD8/AIF. Overexpression of this gene has been shown to induce apoptosis. The expression of this gene is found to be induced by tumor suppressor protein p53 in colon caner cells. The protein encoded by this gene has significant homology to NADH oxidoreductases and the apoptosis-inducing factor PDCD8/AIF. Overexpression of this gene has been shown to induce apoptosis. The expression of this gene is found to be induced by tumor suppressor protein p53 in colon caner cells.

Gene Name: Apoptosis-inducing factor, mitochondrion-associated, 2

Alternative Symbols: AMID, FSP1, PRG3

Protein Name: Apoptosis-inducing factor 2

Molecular Weight: 40kDa

Gene ID: 84883

NCBI Accession: NP_116186

UniProt: Q9BRQ8