GLRA1 antibody (Middle Region)

Catalog No. ABIN2792243

The Rabbit Polyclonal anti-GLRA1 antibody is suitable to detect GLRA1 in samples from Human, Rat, Mouse, Dog, Cow, Horse, Rabbit, Zebrafish (Danio rerio) and Guinea Pig. It has been validated for WB.

Quick Overview for GLRA1 antibody (Middle Region) (ABIN2792243)

Target: GLRA1 (Glycine Receptor, alpha 1 (GLRA1))

Reactivity: Human, Rat, Mouse, Dog, Cow, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLRA1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GLRA1 Antibody

Binding Specificity: Middle Region

Purpose: GLRA1 Antibody - middle region

Sequence: TMNDLIFEWQ EQGAVQVADG LTLPQFILKE EKDLRYCTKH YNTGKFTCIE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against GLRA1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GLRA1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GLRA1

Target: GLRA1 (Glycine Receptor, alpha 1 (GLRA1))

Alternative Name: GLRA1

Background:

Targeted Subunit: alpha-1

Background Information: The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).

Gene Name: Glycine receptor, alpha 1

Alternative Symbols: STHE, HKPX1

Protein Name: Glycine receptor subunit alpha-1

Molecular Weight: 51kDa

Gene ID: 2741

NCBI Accession: NP_000162

UniProt: P23415

Pathways: Synaptic Membrane