GLRA1 antibody (Middle Region)

Catalog No. ABIN2792243

Product Details anti-GLRA1 Antibody

Target: GLRA1 (Glycine Receptor, alpha 1 (GLRA1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Zebrafish (Danio rerio), Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLRA1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TMNDLIFEWQ EQGAVQVADG LTLPQFILKE EKDLRYCTKH YNTGKFTCIE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against GLRA1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GLRA1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 449 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GLRA1

Target: GLRA1 (Glycine Receptor, alpha 1 (GLRA1))

Alternative Name: GLRA1 (GLRA1 Products)

Synonyms: GLYRA1 antibody, HKPX1 antibody, STHE antibody, [a]Z1 antibody, B230397M16Rik antibody, nmf11 antibody, oscillator antibody, ot antibody, spasmodic antibody, spd antibody, glycine receptor alpha 1 antibody, glycine receptor, alpha 1 antibody, glycine receptor, alpha 1 subunit antibody, GLRA1 antibody, Glra1 antibody, glra1 antibody

Background: The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).
Alias Symbols: STHE
Protein Size: 449

Molecular Weight: 51 kDa

Gene ID: 2741

NCBI Accession: NM_000171, NP_000162

UniProt: P23415

Pathways: Synaptic Membrane