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CHM antibody (Choroideremia (Rab Escort Protein 1)) (N-Term) Primary Antibody

CHM Reactivity: Human, Horse WB Host: Rabbit Polyclonal unconjugated
Pubmed (1)
Catalog No. ABIN2792245
$389.00
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100 μL
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  • Target
    CHM
    Binding Specificity
    N-Term
    • 16
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Reactivity
    Human, Horse
    • 39
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    Host
    Rabbit
    Clonality
    Polyclonal
    Conjugate
    This CHM antibody is un-conjugated
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Application
    Western Blotting (WB)
    • 30
    • 21
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Sequence
    LHVDSRSYYG GNWASFSFSG LLSWLKEYQE NSDIVSDSPV WQDQILENEE
    Predicted Reactivity
    Horse: 80%, Human: 100%
    Characteristics
    This is a rabbit polyclonal antibody against CHM. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human CHM
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 653 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ishiguro, Yamamoto, Fujita, Akasu, Kobayashi, Moriya: "Effect of a clinical pathway after laparoscopic surgery for colorectal cancer." in: Hepato-gastroenterology, Vol. 55, Issue 85, pp. 1315-9, 2008 (PubMed).

  • Target
    CHM
    Alternative Name
    CHM (CHM Antibody Abstract)
    Synonyms
    CHM, REP1, DXS540, GGTA, HSD-32, REP-1, TCD, DKFZp459K2154, tcd, ggta, rep-1, dxs540, hsd-32, MGC68578, Rep-1, chm, chm-a, chm-b, chml, CHM, Rab escort protein 1, choroideremia (Rab escort protein 1), choroideremia (Rab escort protein 1) L homeolog, choroidermia (RAB escort protein 1), choroideremia (Rab escort protein 1) S homeolog, CHM, chm, chm.L, Chm, chm.S
    Background
    CHM binds unprenylated Rab proteins, presents it to the catalytic Rab GGTase dimer, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.The choroideremia gene encodes for a protein, the Rab escort protein-1 (REP1), which is involved in membrane trafficking.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: DXS540, FLJ38564, GGTA, HSD-32, MGC102710, REP-1, TCD
    Protein Interaction Partner: UBC, RAB1B, RAB32, RAB14, RAB3D, RAB7A, RAB18, RAB5B, RAB6A, RAB4A, RAB3B, RAB3A, RAB5A, RAB1A,
    Protein Size: 653
    Molecular Weight
    73 kDa
    Gene ID
    1121
    NCBI Accession
    NM_000390, NP_000381
    UniProt
    P24386
    Pathways
    Sensory Perception of Sound
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