GDI2 antibody (C-Term)

Catalog No. ABIN2792268

This Rabbit Polyclonal antibody specifically detects GDI2 in WB. It exhibits reactivity toward Human, Mouse, Horse, Sheep and Guinea Pig.

Quick Overview for GDI2 antibody (C-Term) (ABIN2792268)

Target: GDI2 (GDP Dissociation Inhibitor 2 (GDI2))

Reactivity: Human, Mouse, Horse, Sheep, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDI2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GDI2 Antibody

Binding Specificity: C-Term

Sequence: EPEKEIRPAL ELLEPIEQKF VSISDLLVPK DLGTESQIFI SRTYDATTHF

Predicted Reactivity: Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 92%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against GDI2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GDI2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 445 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GDI2

Target: GDI2 (GDP Dissociation Inhibitor 2 (GDI2))

Alternative Name: GDI2

Background: GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements.GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements.
Alias Symbols: RABGDIB
Protein Interaction Partner: HUWE1, UBC, SUMO2, DUT, BAG3, IQCB1, GLRA2, FN1, SMURF1, RAB1A, RAB11B, AIP, ISG15, SIRT7, ELAVL1, Rab5c, Cdk1, Mapk13, RAB24, RAB11A, RAB9A, RAB5A, RAB4A, RAB2A, RAB8A,
Protein Size: 445

Molecular Weight: 51 kDa

Gene ID: 2665

NCBI Accession: NM_001494, NP_001485

UniProt: P50395