HTR2C antibody (N-Term)

Catalog No. ABIN2792274

This Rabbit Polyclonal antibody specifically detects HTR2C in WB. It exhibits reactivity toward Human, Rat, Mouse, Horse, Pig and Rabbit.

Quick Overview for HTR2C antibody (N-Term) (ABIN2792274)

Target: HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))

Reactivity: Human, Rat, Mouse, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HTR2C antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HTR2C Antibody

Binding Specificity: N-Term

Purpose: HTR2C Antibody - N-terminal region

Sequence: SPVAAIVTDI FNTSDGGRFK FPDGVQNWPA LSIVIIIIMT IGGNILVIMA

Predicted Reactivity: Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against HTR2C. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HTR2C

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HTR2C

Target: HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))

Alternative Name: HTR2C

Background:

Background Information: This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with g proteins that activate a phosphatidylinositol . calcium second messenger system.

Gene Name: 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled

Alternative Symbols: HTR1C, 5-HT1C, 5-HT2C, 5HTR2C, 5-HTR2C

Protein Name: 5-hydroxytryptamine receptor 2C

Molecular Weight: 52kDa

Gene ID: 3358

NCBI Accession: NP_000859

UniProt: P28335

Pathways: Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour