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Serotonin Receptor 3A antibody (HTR3A) (N-Term) Primary Antibody

HTR3A Reactivity: Human, Mouse, Rat, Cow, Dog, Horse IHC, WB Host: Rabbit Polyclonal unconjugated
Pubmed (1)
Catalog No. ABIN2792275
$389.00
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100 μL
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  • Target See all Serotonin Receptor 3A (HTR3A) Antibodies
    Serotonin Receptor 3A (HTR3A)
    Binding Specificity
    • 15
    • 10
    • 9
    • 9
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 71
    • 17
    • 10
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Horse
    Host
    • 64
    • 7
    • 1
    Rabbit
    Clonality
    • 71
    • 1
    Polyclonal
    Conjugate
    • 28
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Serotonin Receptor 3A antibody is un-conjugated
    Application
    • 48
    • 40
    • 14
    • 13
    • 10
    • 10
    • 6
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB)
    Sequence
    LLLPTLLAQG EARRSRNTTR PALLRLSDYL LTNYRKGVRP VRDWRKPTTV
    Predicted Reactivity
    Cow: 78%, Dog: 78%, Horse: 91%, Human: 100%, Mouse: 78%, Rat: 78%
    Characteristics
    This is a rabbit polyclonal antibody against HTR3A. It was validated on Western Blot using a cell lysate as a positive control.
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human HTR3A
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 478 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Rinaldi, Chiaravalli, Mian, Zucca, Tibiletti, Capella, Bertoni: "Serotonin receptor 3A expression in normal and neoplastic B cells." in: Pathobiology : journal of immunopathology, molecular and cellular biology, Vol. 77, Issue 3, pp. 129-35, 2010 (PubMed).

  • Target
    Serotonin Receptor 3A (HTR3A)
    Alternative Name
    HTR3A (HTR3A Products)
    Synonyms
    MGC52789, HTR3A, 5-HT3, 5HT3R, HTR3, 5-HT-3, 5-HT3A, 5-HT3R, 5HT3, Htr3, 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic L homeolog, 5-hydroxytryptamine receptor 3A, 5-hydroxytryptamine (serotonin) receptor 3A, htr3a.L, HTR3A, Htr3a
    Background
    HTR3A belongs to the ligand-gated ion channel receptor superfamily. It is the subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.
    Alias Symbols: HTR3, 5HT3R, 5-HT-3, 5-HT3A, 5-HT3R
    Protein Interaction Partner: HSPA5, CANX,
    Protein Size: 478
    Molecular Weight
    55 kDa
    Gene ID
    3359
    NCBI Accession
    NM_000869, NP_000860
    UniProt
    P46098
    Pathways
    Synaptic Membrane
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