MMP2 antibody (C-Term)

Catalog No. ABIN2792308

This anti-MMP2 antibody is a Rabbit Polyclonal antibody detecting MMP2 in WB and IHC. Suitable for Human, Rat, Mouse, Rabbit, Cow, Dog, Horse, Guinea Pig and Sheep. This Primary Antibody has been cited in 1 publication.

Quick Overview for MMP2 antibody (C-Term) (ABIN2792308)

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Dog, Horse, Guinea Pig, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MMP2 Antibody

Binding Specificity: C-Term

Sequence: AWNAIPDNLD AVVDLQGGGH SYFFKGAYYL KLENQSLKSV KFGSIKSDWL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against MMP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MMP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 660 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-MMP2 antibody (ABIN2792308)

Puttabyatappa, Irwin, Martin, Mesquitta, Veiga-Lopez, Padmanabhan: "Developmental Programming: Gestational Exposure to Excess Testosterone Alters Expression of Ovarian Matrix Metalloproteases and Their Target Proteins" in: Reproductive sciences (Thousand Oaks, Calif.), pp. 1933719117697130, (2017) (PubMed).

Target Details for MMP2

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Alternative Name: MMP2

Background: MMP-2 is involved in the cleavage of gelatin type I and collagen types IV, V, VII, X.
Alias Symbols: CLG4, MONA, CLG4A, TBE-1, MMP-II
Protein Interaction Partner: HSP90AA1, CAND1, ITGB1, ITGAV, USP12, OSBPL10, SPOCK1, BACE1, PZP, MMP25, CLDN1, KISS1, MMP17, TIMP4, EPHB2, CXCL12, MMP14, BCAN, LCN2, TIMP1, TGFB1, TIMP3, TIMP2, THBS2, THBS1, CCL7, ACAN, LGALS3, IL1B, IGFBP3, FGFR1, DCN, COL18A1, COL6A3, COL1A1, COL7A1
Protein Size: 660

Molecular Weight: 74 kDa

Gene ID: 4313

NCBI Accession: NM_004530, NP_004521

UniProt: P08253

Pathways: Activation of Innate immune Response