IRF2 antibody (N-Term)

Catalog No. ABIN2792534

The Rabbit Polyclonal anti-IRF2 antibody is suitable to detect IRF2 in samples from Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Sheep and Zebrafish (Danio rerio). It has been validated for WB and IHC.

Quick Overview for IRF2 antibody (N-Term) (ABIN2792534)

Target: IRF2 (Interferon Regulatory Factor 2 (IRF2))

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-IRF2 Antibody

Binding Specificity: N-Term

Purpose: IRF2 Antibody - N-terminal region

Sequence: APLFRNRAIH TGKHQPGVDK PDPKTWKANF RCAMNSLPDI EEVKDKSIKK

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rat: 100%, Sheep: 92%, Zebrafish: 90%

Characteristics: This is a rabbit polyclonal antibody against IRF2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IRF2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for IRF2

Target: IRF2 (Interferon Regulatory Factor 2 (IRF2))

Alternative Name: IRF2

Background:

Background Information: IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4.

Gene Name: Interferon regulatory factor 2

Alternative Symbols: IRF-2

Protein Name: Interferon regulatory factor 2

Molecular Weight: 39kDa

Gene ID: 3660

NCBI Accession: NP_002190

UniProt: P14316