IRF2 antibody (N-Term)

Catalog No. ABIN2792534

Product Details anti-IRF2 Antibody

Target: IRF2 (Interferon Regulatory Factor 2 (IRF2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Sheep, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: APLFRNRAIH TGKHQPGVDK PDPKTWKANF RCAMNSLPDI EEVKDKSIKK

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rat: 100%, Sheep: 92%, Zebrafish: 90%

Characteristics: This is a rabbit polyclonal antibody against IRF2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IRF2

Application Details

Application Notes: WB Suggested Anti-IRF2 Antibody Titration: 0.2-1 µg/mL
Positive Control: Jurkat cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 349 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IRF2

Target: IRF2 (Interferon Regulatory Factor 2 (IRF2))

Alternative Name: IRF2 (IRF2 Products)

Synonyms: IRF-2 antibody, 9830146E22Rik antibody, AI646973 antibody, Irf-2 antibody, irf2b antibody, zgc:103451 antibody, irf-2 antibody, wu:fc74h04 antibody, zgc:76951 antibody, interferon regulatory factor 2 antibody, interferon regulatory factor 2 L homeolog antibody, interferon regulatory factor 2a antibody, IRF2 antibody, Irf2 antibody, irf2 antibody, irf2.L antibody, irf2a antibody

Background: IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4.
Alias Symbols: IRF-2
Protein Interaction Partner: IRF1, SUMO2, SUMO3, PRDM1, MDM2, FKBP7, HSP90AA1, APP, IRF2BP2, IRF2BP1, UBC, FOXK1, IRF2BPL, HCFC2, ATG7, AP5Z1, PPP3CB, PPP3CA, FOXK2, HCFC1, KAT2B, EP300, IRF8, STAT1, RELA, NFKB1, HMGN1, HMGB1, CSNK2A1, BRD7, PRKACA, KAT2A,
Protein Size: 349

Molecular Weight: 39 kDa

Gene ID: 3660

NCBI Accession: NM_002199, NP_002190

UniProt: P14316