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SMAD3 antibody (N-Term)

This Rabbit Polyclonal antibody specifically detects SMAD3 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Zebrafish (Danio rerio) and Guinea Pig.
Catalog No. ABIN2792537
$429.69
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Quick Overview for SMAD3 antibody (N-Term) (ABIN2792537)

Target

See all SMAD3 Antibodies
SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

Reactivity

  • 274
  • 126
  • 100
  • 13
  • 12
  • 9
  • 7
  • 7
  • 6
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
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  • 1
Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Guinea Pig

Host

  • 259
  • 29
  • 1
Rabbit

Clonality

  • 219
  • 70
Polyclonal

Conjugate

  • 140
  • 17
  • 13
  • 11
  • 10
  • 7
  • 6
  • 6
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  • 6
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  • 4
  • 4
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  • 3
  • 1
  • 1
  • 1
  • 1
This SMAD3 antibody is un-conjugated

Application

  • 238
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  • 91
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  • 57
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  • 38
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  • 10
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Western Blotting (WB), Immunohistochemistry (IHC)
  • Binding Specificity

    • 54
    • 49
    • 29
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    • 12
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    • 11
    • 8
    • 6
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    • 2
    • 1
    • 1
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    • 1
    • 1
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    N-Term

    Purpose

    SMAD3 Antibody - N-terminal region

    Sequence

    FTPPIVKRLL GWKKGEQNGQ EEKWCEKAVK SLVKKLKKTG QLDELEKAIT

    Cross-Reactivity

    Dog (Canine), Chicken, Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)

    Predicted Reactivity

    Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

    Characteristics

    This is a rabbit polyclonal antibody against SMAD3. It was validated on Western Blot and immunohistochemistry.

    Purification

    Protein A purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human SMAD3
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1.0 mg/mL

    Buffer

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    prevent freeze-thaw cycles

    Storage

    4 °C,-20 °C

    Storage Comment

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Target

    SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

    Alternative Name

    SMAD3

    Background

    Background Information: SMAD3 is a member of Smad family proteins. SMAD family is known to be important cytoplasmic mediators of signals from the transforming growth factor-beta (TGF-beta) receptor serine/threonine kinases.

    Gene Name: SMAD family member 3

    Alternative Symbols: LDS3, LDS1C, MADH3, JV15-2, HSPC193, HsT17436

    Molecular Weight

    48kDa

    Gene ID

    4088

    NCBI Accession

    NP_005893

    UniProt

    P84022

    Pathways

    Cell Division Cycle, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagy
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