CREB5 antibody (N-Term)

Catalog No. ABIN2792570

Product Details anti-CREB5 Antibody

Target: CREB5 (CAMP Responsive Element Binding Protein 5 (CREB5))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CREB5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: CSLEHEFRKA QEEESSKRNI SMHNAVGGAM TGPGTHQLSS ARLPNHDTNV

Cross-Reactivity: Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CREB5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CREB5

Application Details

Application Notes: WB Suggested Anti-CREB5 Antibody Titration: 1.25 µg/mL
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 475 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CREB5

Target: CREB5 (CAMP Responsive Element Binding Protein 5 (CREB5))

Alternative Name: CREB5 (CREB5 Products)

Synonyms: CREB5 antibody, CRE-BPA antibody, Crebpa antibody, D430026C09Rik antibody, RGD1566107 antibody, cAMP responsive element binding protein 5 antibody, CREB5 antibody, creb5 antibody, Creb5 antibody

Background: CREB5 belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. This protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: CRE-BPA
Protein Interaction Partner: KRTAP10-5, KRTAP10-11, KRTAP10-1, KRTAP10-9, KRTAP10-7, MGAT5B, KRT40, RIMBP3, KRTAP4-2, KRTAP9-4, KRTAP9-2, KRTAP3-2, KRTAP4-12, TSGA10, ADAMTSL4, EFEMP2, MTUS2, RBPMS, SPRY2, SPRY1, RGS20, FOSL1, TRIP6, TRAF2, MDFI, KRT15, KIFC3, FOSL2, FOS, COL8A1, TRI
Protein Size: 475

Molecular Weight: 53 kDa

Gene ID: 9586

NCBI Accession: NM_182899, NP_878902

UniProt: Q02930

Pathways: Thyroid Hormone Synthesis