TCF4 antibody (N-Term)

Catalog No. ABIN2792579

The Rabbit Polyclonal anti-TCF4 antibody is suitable to detect TCF4 in samples from Human, Mouse, Horse and Guinea Pig. It has been validated for WB.

Quick Overview for TCF4 antibody (N-Term) (ABIN2792579)

Target: TCF4 (Transcription Factor 4 (TCF4))

Reactivity: Human, Mouse, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCF4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TCF4 Antibody

Binding Specificity: N-Term

Purpose: TCF4 Antibody - N-terminal region

Sequence: MHHQQRMAAL GTDKELSDLL DFSAMFSPPV SSGKNGPTSL ASGHFTGSNV

Cross-Reactivity: Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%

Characteristics: This is a rabbit polyclonal antibody against TCF4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TCF4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TCF4

Target: TCF4 (Transcription Factor 4 (TCF4))

Alternative Name: TCF4

Background:

Background Information: TCF4 encodes transcription factor 4, a basic helix-turn-helix transcription factor. The protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. TCF4 is expressed predominantly in pre-B-cells, although it is found in other tissues as well.

Gene Name: Transcription factor 4

Alternative Symbols: E2-2, ITF2, PTHS, SEF2, CDG2T, FECD3, ITF-2, SEF-2, TCF-4, SEF2-1, SEF2-1A, SEF2-1B, SEF2-1D, bHLHb19

Protein Name: Transcription factor 4

Molecular Weight: 71kDa

Gene ID: 6925

NCBI Accession: NP_003190

UniProt: P15884

Pathways: WNT Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus