HOXD10 antibody (Middle Region)

Catalog No. ABIN2792662

This Rabbit Polyclonal antibody specifically detects HOXD10 in WB. It exhibits reactivity toward Mouse, Rat, Cow, Dog, Horse, Pig and Rabbit.

Quick Overview for HOXD10 antibody (Middle Region) (ABIN2792662)

Target: HOXD10 (Homeobox D10 (HOXD10))

Reactivity: Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXD10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HOXD10 Antibody

Binding Specificity: Middle Region

Purpose: HOXD10 Antibody - middle region

Sequence: NPEVPVPGYF RLSQTYATGK TQEYNNSPEG SSTVMLQLNP RGAAKPQLSA

Cross-Reactivity: Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against HOXD10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HOXD10

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HOXD10

Target: HOXD10 (Homeobox D10 (HOXD10))

Alternative Name: HOXD10

Background:

Background Information: HOXD10 is the sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as 'rocker-bottom foot' deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Homeobox D10

Alternative Symbols: HOX4, HOX4D, HOX4E, Hox-4.4

Protein Name: Homeobox protein Hox-D10

Molecular Weight: 38kDa

Gene ID: 3236

NCBI Accession: NP_002139

UniProt: P28358