BSCL2 antibody (N-Term)

Catalog No. ABIN2796949

Product Details anti-BSCL2 Antibody

Target: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Binding Specificity: AA 78-107, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BSCL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: Rabbit Anti-Human BSCL2 (N-term) Antibody

Immunogen: This BSCL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-107 amino acids from the N-terminal region of human BSCL2.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100BSCL2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.350 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for BSCL2

Target: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Alternative Name: BSCL2 (BSCL2 Products)

Synonyms: GNG3LG antibody, HMN5 antibody, SPG17 antibody, 2900097C17Rik antibody, AI046355 antibody, Gng3lg antibody, BSCL2, seipin lipid droplet biogenesis associated antibody, Berardinelli-Seip congenital lipodystrophy 2 (seipin) antibody, BSCL2 antibody, Bscl2 antibody

Background:

Target Description: This gene encodes protein seipin, which is located in the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Symbol: BSCL2

Molecular Weight: 44392 Da

Gene ID: 26580

UniProt: Q96G97