BSCL2 antibody (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin)) (C-Term)

Details for Product anti-BSCL2 Antibody No. ABIN2784048
Antigen
Epitope
C-Term
9
9
8
3
2
2
2
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
32
2
2
1
1
1
1
1
Host
Rabbit
26
6
1
Clonality
Polyclonal
Conjugate
This BSCL2 antibody is un-conjugated
2
2
2
2
2
2
Application
Western Blotting (WB)
33
22
19
2
1
1
Options
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human BSCL2
Blocking Peptide Blocking peptide for this product available: ABIN973902
Sequence QEESTPQSDV TEDGESPEDP SGTEGQLSEE EKPDQQPLSG EEELEPEAS
Predicted Reactivity Cow: 86%, Dog: 86%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
Characteristics This is a rabbit polyclonal antibody against BSCL2. It was validated on Western Blot.
Purification Affinity Purified
Antigen
Alternative Name BSCL2 (BSCL2 Antibody Abstract)
Background This gene encodes protein seipin, which is located in the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: GNG3LG, HMN5, MGC4694, SPG17
Protein Interaction Partner: SMLR1, SMIM3, PLEKHF2, TMEM19, NSG1, SUMO2, SUMO3, Hoxa1, UBC, CANX, USE1,
Protein Size: 462
Molecular Weight 51 kDa
Gene ID 26580
NCBI Accession NM_001122955, NP_001116427
UniProt Q96G97
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 462 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Image no. 1 for anti-Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2) (C-Term) antibody (ABIN2784048) WB Suggested Anti-BSCL2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Pos...
Image no. 2 for anti-Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2) (C-Term) antibody (ABIN2784048) WB Suggested Anti-BSCL2 Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 Posit...