BSCL2 antibody (C-Term)

Catalog No. ABIN928313

Product Details anti-BSCL2 Antibody

Target: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BSCL2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: BSCL2 antibody was raised in rabbit using the C terminal of BSCL2 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

BSCL2 Blocking Peptide, catalog no. 33R-7521, is also available for use as a blocking control in assays to test for specificity of this BSCL2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for BSCL2

Target: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Alternative Name: BSCL2 (BSCL2 Products)

Synonyms: GNG3LG antibody, HMN5 antibody, SPG17 antibody, 2900097C17Rik antibody, AI046355 antibody, Gng3lg antibody, BSCL2, seipin lipid droplet biogenesis associated antibody, Berardinelli-Seip congenital lipodystrophy 2 (seipin) antibody, BSCL2 antibody, Bscl2 antibody

Background: This gene encodes protein seipin, which is located in the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Synonyms: Polyclonal BSCL2 antibody, Anti-BSCL2 antibody, Berardinelli-Seip congenital lipodystrophy 2, seipin antibody, GNG3LG antibody, HMN5 antibody, MGC4694 antibody, SPG17 antibody.