BSCL2 antibody (AA 50-150)

Catalog No. ABIN7265874

The Rabbit Polyclonal anti-BSCL2 antibody (ABIN7265874) specifically detects BSCL2 in WB, IHC and IF. The antibody is reactive with Human samples.

Quick Overview for BSCL2 antibody (AA 50-150) (ABIN7265874)

Target: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BSCL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-BSCL2 Antibody

Binding Specificity: AA 50-150

Purpose: BSCL2 Rabbit pAb

Sequence: GSFYYSYMPT VSHLSPVHFY YRTDCDSSTT SLCSFPVANV SLTKGGRDRV LMYGQPYRVT LELELPESPV NQDLGMFLVT ISCYTRGGRI ISTSSRSVML H

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human BSCL2 (NP_116056.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BSCL2

Target: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Alternative Name: BSCL2

Background: This gene encodes the multi-pass transmembrane protein protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2).,BSCL2,GNG3LG,HMN5,PELD,SPG17,seipin,Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Obesity,Neuroscience,Neurodegenerative Diseases,Cardiovascular,BSCL2

Molecular Weight: 32kDa/44kDa/51kDa

Gene ID: 26580

UniProt: Q96G97