KREMEN2 antibody (Center)

Catalog No. ABIN2798011

Product Details anti-KREMEN2 Antibody

Target: KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))

Binding Specificity: AA 248-276, Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KREMEN2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit Anti-Human KREMEN2 (Center) Antibody

Immunogen: This KREMEN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-276 amino acids from the Central region of human KREMEN2.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000KREMEN2 Antibody (Center) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for KREMEN2

Target: KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))

Alternative Name: KREMEN2 (KREMEN2 Products)

Synonyms: krm2 antibody, KREMEN2 antibody, MGC147633 antibody, KRM2 antibody, 2900054E04Rik antibody, Krm2 antibody, kringle containing transmembrane protein 2 S homeolog antibody, kringle containing transmembrane protein 2 antibody, kremen2.S antibody, KREMEN2 antibody, kremen2 antibody, Kremen2 antibody

Background:

Target Description: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.

Gene Symbol: KREMEN2

Molecular Weight: 48849 Da

Gene ID: 79412

UniProt: Q8NCW0

Pathways: WNT Signaling