MCPH1 antibody (N-Term)

Catalog No. ABIN2798488

This Rabbit Polyclonal antibody specifically detects MCPH1 in WB. It exhibits reactivity toward Human.

Quick Overview for MCPH1 antibody (N-Term) (ABIN2798488)

Target: MCPH1 (Microcephalin 1 (MCPH1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCPH1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MCPH1 Antibody

Binding Specificity: AA 104-133, N-Term

Purpose: Rabbit Anti-Human MCPH1 (N-term) Antibody

Immunogen: This MCPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the N-terminal region of human MCPH1.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000MCPH1 Antibody (N-term) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for MCPH1

Target: MCPH1 (Microcephalin 1 (MCPH1))

Alternative Name: MCPH1

Background:

Target Description: This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.

Gene Symbol: MCPH1

Molecular Weight: 92877 Da

Gene ID: 79648

UniProt: Q8NEM0

Pathways: Stem Cell Maintenance