QPRT antibody (C-Term)
Quick Overview for QPRT antibody (C-Term) (ABIN2798571)
Target
See all QPRT AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 206-234, C-Term
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Purpose
- Rabbit Anti-Human QPRT (C-term) Antibody
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Immunogen
- This QPRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-234 amino acids from the C-terminal region of human QPRT.
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Isotype
- Ig Fraction
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Application Notes
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50QPRT Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Storage
- 4 °C,-20 °C
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Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- QPRT (Quinolinate Phosphoribosyltransferase (QPRT))
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Alternative Name
- QPRT
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Background
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Target Description: This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease.
Gene Symbol: QPRT
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Molecular Weight
- 30846 Da
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Gene ID
- 23475
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UniProt
- Q15274
Target
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