QPRT antibody (AA 1-297)

Catalog No. ABIN5775978

This Mouse Monoclonal antibody specifically detects QPRT in WB, ELISA, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for QPRT antibody (AA 1-297) (ABIN5775978)

Target: QPRT (Quinolinate Phosphoribosyltransferase (QPRT))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This QPRT antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT24C4

Product Details anti-QPRT Antibody

Binding Specificity: AA 1-297

Purpose: Human QPRT antibody

Purification: Purified

Immunogen: Recombinant human QPRT (1-297aa) purified from E. coli

Isotype: IgG2a kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for QPRT

Target: QPRT (Quinolinate Phosphoribosyltransferase (QPRT))

Alternative Name: QPRT

Background: Quinolinate phosphoribosyltransferase, also known as QPRT, is a major enzyme in the catabolism of quinolinate. It is an intermediate in the tryptophannicotinamide adenine dinucleotide (NAD) pathway, leading to the production of nicotinic acid, carbon dioxide and pyrophosphate. Elevation of QPRT levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease.

NCBI Accession: NP_055113