QPRT antibody (AA 1-297)

Catalog No. ABIN7269781

This Rabbit Polyclonal antibody specifically detects QPRT in WB. It exhibits reactivity toward Human.

Quick Overview for QPRT antibody (AA 1-297) (ABIN7269781)

Target: QPRT (Quinolinate Phosphoribosyltransferase (QPRT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This QPRT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-QPRT Antibody

Binding Specificity: AA 1-297

Purpose: QPRT Rabbit pAb

Sequence: MDAEGLALLL PPVTLAALVD SWLREDCPGL NYAALVSGAG PSQAALWAKS PGVLAGQPFF DAIFTQLNCQ VSWFLPEGSK LVPVARVAEV RGPAHCLLLG ERVALNTLAR CSGIASAAAA AVEAARGAGW TGHVAGTRKT TPGFRLVEKY GLLVGGAASH RYDLGGLVMV KDNHVVAAGG VEKAVRAARQ AADFALKVEV ECSSLQEAVQ AAEAGADLVL LDNFKPEELH PTATVLKAQF PSVAVEASGG ITLDNLPQFC GPHIDVISMG MLTQAAPALD FSLKLFAKEV APVPKIH

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-297 of human QPRT (NP_055113.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for QPRT

Target: QPRT (Quinolinate Phosphoribosyltransferase (QPRT))

Alternative Name: QPRT

Background: This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants.,QPRT,HEL-S-90n,QPRTase,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,QPRT

Molecular Weight: 30kDa

Gene ID: 23475

UniProt: Q15274