CD70 antibody (Center)

Catalog No. ABIN2798728

This Rabbit Polyclonal antibody specifically detects CD70 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for CD70 antibody (Center) (ABIN2798728)

Target: CD70 (CD70 Molecule (CD70))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD70 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CD70 Antibody

Binding Specificity: AA 72-101, Center

Purpose: Rabbit Anti-Human CD70 (Center) Antibody

Immunogen: This CD70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the Central region of human CD70.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50CD70 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.500 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for CD70

Target: CD70 (CD70 Molecule (CD70))

Alternative Name: CD70

Background:

Target Description: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

Gene Symbol: CD70

Molecular Weight: 21118 Da

Gene ID: 970

UniProt: P32970

Pathways: Cancer Immune Checkpoints