Septin 5 antibody (N-Term)
Quick Overview for Septin 5 antibody (N-Term) (ABIN2798741)
Target
See all Septin 5 (SEPT5) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-30, N-Term
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Purpose
- Rabbit Anti-Human SEPT5 (N-term) Antibody
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Immunogen
- This SEPT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SEPT5.
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Isotype
- Ig Fraction
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Application Notes
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50Western blot analysis of lysate from human brain tissue lysate, using SEPT5 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Storage
- 4 °C,-20 °C
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Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- Septin 5 (SEPT5)
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Alternative Name
- SEPT5
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Background
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Target Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB, platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq].
Gene Symbol: SEPT5
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Molecular Weight
- 42777 Da
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Gene ID
- 5413
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UniProt
- Q99719
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Pathways
- Synaptic Vesicle Exocytosis
Target
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